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पूर्वोत्तर क्षेत्रीय विज्ञान एवं प्रौद्योगिकी संस्थान   
North Eastern Regional Institute of Science and Technology 
deemed-to-be-university under the Ministry of Education, Govt. of India
Nirjuli - 791109, Arunachal Pradesh 
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  • Dr. Nagendra Nath Yadav
faculties

Dr. Nagendra Nath Yadav

Assistant Professor

Total synthesis of natural products, Development of new synthetic methodology and their application for the synthesis of biologically active molecules, asymmetric synthesis, medicinal chemistry, bio-organic chemistry, drug discovery, API (Active Pharmaceutical Ingredient) synthesis, process research and development, green chemistry, aziridine chemistry.

e-mail: nny[AT]nerist(dot)ac(dot)in, nnyiict[AT]gmail.com
Phone(EPBX/Office): +91-360-2257401 to 408; Ext. 7134

  • Professional Background
  • Honors and Awards
  • Educational Details
  • Administrative Background
  • Sponsored Research Projects
  • Memberships in Professional bodies
  • Teaching Engagements
  • PROJECTS AND THESIS SUPERVISED/ CURRENTLY SUPERVISING
  • PHDS SUPERVISED
  • Participation in short term courses
  • Publications
  • MISCELLANEOUS
From To Designation Organisation
Novemver, 2016 Till date Assistant Professor NERIST (Deemed-to-be-University Under MoE, Govt. of India)
March, 2015 October 2016 Post-doctoral Research Assistant  (Supervisor – Prof. Hyun-Joon Ha) Hankuk University of Foreign Studies, Yongin, Korea
April, 2013 February 2015 Research Scientist Process Research & Development Division, Sai Life Sciences Ltd., Hyderabad, India
March 2012 March 2013 Junior  Research Scientist Research & Development Division, Biophore Pharma Ltd., Hyderabad, India
Award Institute Year
Postdoctoral Research Fellowship Hankuk University of Foreign Studies, Yongin, Korea       2015
Inspire Faculty Department of Science & Technology (DST), New Delhi, India       2012
Senior Research Fellowship (SRF) Council for Scientific and Industrial Research (CSIR), New Delhi, India       2008
Junior Research Fellowship (JRF) Council for Scientific and Industrial Research (CSIR), New Delhi, India       2006
Graduate Aptitude Test in Engineering (GATE) IIT Kharagpur (MHRD, India)       2006
Degree Subject University Year
Ph.D   Chemistry Indian Institute of Chemical Technology (IICT)/ JNTU, Hyderabad, India (Supervisor: Dr. J. S. Yadav)

2014

 

  
M.Sc. Chemistry (Organic) DDU Gorakhpur University 2005
From To Designation Organisation
July 2018 Till date Lab Incharge PG Lab-II NERIST
March 2021 Till date Lab Incharge PG Lab-I NERIST
Topic Funding Agency Year
     
 
Title Course Code Module Semester
Biochemistry     CY 3203 B. Sc. (Forestry) 1st Year          II
Application of Spectroscopy to Organic Molecules     CY 8004 M. Sc. 2nd Year          I
Natural Products     CY 8006 M. Sc. 2nd Year          I
Organic Chemistry Lab     CY 8152 M. Sc. 2nd Year          I
Chemistry 2     CY 11201 Base 1st Year  
Chemistry 2 Lab     CY 11201 Base 1st Year          II     
Organic  Synthesis     CY 8017 M. Sc. 2nd Year          II
Project Work     CY 8299 M. Sc. 2nd Year          II
Title of Project Names of Students
Synthesis of Protected Glucose Derivatives Mr. Partha P. Nath
Synthesis of Various ortho-Allyl Phenols via Claisen Rearrangement Ms. Pompy Pokhrel
Activation of Quinoline/Isoquinoline for rhe Synthesis of Various Dihydro quinoline/ Isoquinoline derivatives Mr. Hannan Uddin
Synthesis of three membered azaheterocycle Aziridine and its Opening Reaction Mr. Monuranjan Gogoi
Synthesis of key starting material for Natural Products having Deoxypropionate Skeleton Mr. Pranjit Saikia
Preparation of Iodine based oxidising agent and its application in Organic Synthesis Mr. Rinku Dihingia
Study of stabilised and non-stabilised phosphonium ylides and synthesis of alkene by Wittig reaction Mr. Prafulla Kaman
Preparation of Pyridine based oxidising agents and its application in oxidation reaction Ms. Mandita Devi
Three-Component Coupling of Isoquinoline/Quinoline, Dimethyl Acetylenedicarboxylate (DMAD) and Reactive Methylene Compound: A Facile Synthesis of Dihydroisoquinoline/Quinoline Derivative Ms. Rekhajyoti Phukan
Synthesis of Chiral Aziridine and Nucleophilic Ring Opening with Anisole and Imidazole Mr. Nabin Sharma
Synthesis of Chiral Aziridine and Its Ring Opening Reaction with Indole Mr. Hirak Jyoti Bhuyan
Synthesis of Morita-Baylis-Hillman Acetate from P-Nitrobenzaldehyde and Its Substitution Reaction with Active Methylene Compounds Mr. Abhimanyu Nayak
Synthesis of acetate adducts of Baylis-Hillman reaction and Its Reaction with Active Methylene Compounds Mr. Wrishav Rajkhowa
Synthesis of Non-activated Aziridine and Its Ring Opening Reaction with 2-MethylIndole Mr. Debasish Baruah
Synthesis of Morita Baylis-Hillman Acetate from Unsubstituted Aromatic Aldehyde and Its Substitution Reaction with Aniline Mrs. Kalyanee Kalita
Reaction of Morita-Baylis Hillman Acetate with Pyrazolone as Nucleophile: Regioselective Synthesis of 5-Hydroxypyrazoles Ms. Tupu Narzary
Reaction of Morita Baylis-Hillman Acetate with Sodium p-Toluenesulfinate: Regioselective Synthesis of Tosyl Substituted Acrylates Mr. Tenzin Palden
Topic Scholar Name Status of PHD Registration Year
Synthesis of Natural Products from Chiral aziridine and Development of new Synthetic Methodologies Mrs. Archana Pareek Thesis Submitted 2017
Synthesis of Piperidine Ring System and Development of New Synthetic Methods Mr. Sonam Tashi Khom Thesis Submitted 2018
Synthesis of Piperidine alkaloids from Aziridine and development of new synthetic methods Mr. Pranjit Saikia Ongoing 2021
Course Name Sponsored By Date
15th Division of Organic Chemistry (branch organic chemistry) Summer Workshop on NMR Spectroscopy, Geoje, Korea Korean Chemical Society August 24-25, 2015
“Pedagogy Training for Outcome Based Education”, at NERIST NITTTR Bhopal March 16-17, 2017
Workshop on the Role of Local Chapters, at NERIST IIT Kanpur April 29, 2017
Short term course on “Leadership and Team Building in Academia” at NERIST NITTTR – Kolkata Oct 30 to Nov 03, 2017
One week Faculty Development Programme on “DSP & SENSORS” Electronics and ICT Acedemics, Government of India December 10-14, 2018
Four week Orientation programme at UGC HRDC DDU Gorakhpur University Gorakhpur UGC HRDC DDU Gorakhpur University Jan 15 to Feb 11, 2019
One week Faculty Development Programme on topic “Network Security” at NERIST Electronics and ICT Academy IIT Guwahati May 20-24, 2019
One week Faculty Development Programme on topic “Deep Learning and Applications” at NERIST Electronics and ICT Academy IIT Guwahati May 27-31, 2019
One week Faculty Development Programme on topic “Anteena Trends” at NERIST Electronics and ICT Academy IIT Guwahati July 01-05, 2019
Two week Faculty Development Programme on “Impact of Climate change on Water Resources” at NERIST NERIST, Nirjuli, Arunachal Pradesh October 14-25, 2019
One week Faculty Development Programme on topic “ICT Tools for Teaching, Learning Process & Institutes” at NERIST Electronics and ICT Academy January 13-17, 2020
Training Programme on topic “National Level Training Programme on DISASTER MANAGEMENT” at NERIST National Institute of Disaster Management February 27-29, 2020
One week online Faculty Development Programme on topic “Energy and Environment: Conversion, generation, storage and efficient utilization” Dept. of EE and CE, NERIST August 24-28, 2020
Online Training Programme on Digital tools for Writing, Authoring & Reviewing Manuscripts Electronics & ICT Academies, MNIT Jaipur, NIT Patna & IIT Guwahati September 21 to October 02, 2020
Two week UGC sponsored refresher course in Chemistry Chemistry Department, DDU Gorakhpur University, Gorakhpur September 11-24, 2021
One week online Faculty Development Programme on topic “Inculcating Universal Human Values in Technical Education” All India Council for Technical Education (AICTE) October 4 - 8, 2021
  NPTEL-SWAYAM Jan-Apr 2021
International Journals:

  1. Khom, S. T.; Saikia, P.; Yadav, N. N. (Facile synthesis of 3-amino substituted piperidines from L-glutamic acid) Indian Journal of Chemistry 2024, 63, 518 –523.

  2. Pareek, A.; Khom, S. T.; Saikia, P.; Yadav, N. N. (A short and efficient Formal Synthesis of R-Pipecolic Acid from the Ring expansion of Chiral Aziridine) Monatsh Chem 2024, 155, 525-529.

  3. Khom, S. T.; Saikia, P.; Muzaddadi, I. U.; Murugan, A.; Yadav, N. N. (Synthesis of allylamines from Baylis–Hillman acetates using DBU under solvent free condition) Monatsh Chem 2023, 154, 865-871.

  4. V. Thandiayyakone, , A. Murugan, Ijaz U. Muzaddadi, , N. Tayum, , N. N. Yadav, , Pranjit Saikia, , T. Rajkumar, , A. Manohar, M. Chakrabarty (Effects of SbCl5, Ethylamine, Imidazole and 2-Methylimidazole on Redox and Structural Behaviours of Manganese(III) meso-5,10,15,20-tetrakis(4-pyridyl)porphyrin) Asian Journal of Chemistry 2023, 35, 1714-1718.

  5. Suryachandra, D. K.; Tenneti, S.; Yadav, N. N.; Yadav, J. S. (Stereoselective synthesis of C1-C11 fragment of antitumor cyclodepsipeptide (–)-doliculide) Indian Journal of Chemistry 2020, 59B, 376 –384.

  6. Yadav, N. N.; Lee, Y.-G.; Srivastava, N.; Ha, H.-J. (Alkylative Ring-Opening of Bicyclic Aziridinium Ion and Its Application for Alkaloid Synthesis) Frontiers in Chemistry 2019, (7), doi: 10.3389/fchem.2019.00460

  7. Yadav, N. N.; Ha, H.-J.; “Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles”  J. Vis. Exp. (138), e57572, doi:10.3791/57572 (2018)

  8. Yadav, N. N.; Jeong, H; Ha, H.-J.; “Atom-Economical and Metal-Free Synthesis of Multisubstituted Furans from Intramolecular Aziridine Ring Opening” ACS Omega 2017, 2, 7525−7531.

  9. Choi, J.; Yadav, N. N.; Ha, H.-J.; “Preparation of a Stable Bicyclic Aziridinium Ion and Its Ring Expansion toward Piperidine and Azepane”, Asian J. Org. Chem. 2017, 6, 1292 –1307.

  10. Jeong, H; Yadav, N. N.; Ha, H.-J.; “Synthesis of Lacosamide (Vimpat) and Its Derivatives from Aziridine-(2R)-carboxylate”,  SYNTHESIS 2016, 49, 1264–1272.

  11. Yadav, N. N.; Dolfen, J.; Kimpe, N. D.; D’hooghe, M.; Ha, H.-J.; “Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry – Preparation and Synthetic Application of 1-Azoniabicyclo[n.1.0]alkanes”, Adv. Synth. Catal. 2016, 358, 3485–3511.

  12. Yadav, N. N.; Choi, J.; Ha, H.-J.; “One-pot multiple reactions: asymmetric synthesis of 2,6-cis-disubstituted piperidine alkaloids from chiral aziridine”, Org. Biomol. Chem., 2016, 14, 6426-6434.

  13. Yadav, J. S.; Yadav, N. N.; Reddy, B. V. S.; “Studies directed towards the total synthesis of polyether antibiotic ionomycin: asymmetric synthesis of fragments C(24)-C(32) and C(1)-C(23)”, Tetrahedron 2015, 71, 7539-7549.

  14. Yadav, J. S.; Yadav, N. N.; Gupta, M. K., Srivastava, N.; Reddy, B. V. S.; “GaCl3-catalyzed activation of alkynyl glycosides for the synthesis of O-glycosides”, Monatsh Chem 2014, 145, 517-520.

  15. Yadav, J. S.; Yadav, N. N.; “An iterative, facile stereoselective synthesis of C1-C11 fragment of borrelidin via enzymatic desymmetrization strategy”, RSC Advances, 2013, 3, 4024-4032.

  16. Yadav, J. S.; Chary, D. N.; Yadav, N. N.; Sengupta, S.; Reddy, B. V. S. (Enantioselective Total Synthesis of Siphonarienal, Siphonarienone and Pectinatone) Helvetica Chimica Acta 2013, 96, 1968–1977

  17. Yadav, J. S.; Sengupta, S.; Yadav, N. N.; Chary, D. N.; Ghamdi, A. A.; “Stereoselective synthesis of methyl branched chiral deoxypropionate units: A new route for synthesis of insect pheromone (−)-lardolure and (2R,4R,6R,8R) 2,4,6,8-tetramethylundecanoic acid”, Tetrahedron Lett. 2012, 53, 5952–5954.

  18. Yadav, J. S.; Rao, T.S.; Yadav, N. N.; Rao, K. V. R.; Reddy, B. V. S.; Ghamdi, A. K.; “Chemoenzymatic Approach to the Total Synthesis of (+)-Bourgeanic Acid”, SYNTHESIS 2012, 44(5), 788-792.

  19. Reddy, B. V. S.; Yadav, N. N.; Srivastava, N.; Yadav, J. S.; Sridhar, B.; “1,4-Dipolar cycloaddition reactions in ionic liquids: a facile synthesis of 9aH 15H-[1]Benzopyrano[3’,2’:3,4]pyrido[2,1-a]isoquinolines(=9aH 15HBenzo[a][1]benzopyrano [2,3-h]quinolizines”, Helvetica Chim. Acta 2012, 95, 76–86.

  20. Yadav, J. S.; Yadav, N. N.; Rao, T. S.; Reddy, B. V. S.; Ghamdi, A. K.; “Enantioselective total synthesis of (+)-vittatalactone”, Eur. J. Org. Chem. 2011, 4603–4608.

  21. Yadav, J. S.; Gupta, M. K.; Jain, R.; Yadav, N. N.; Reddy, B. V. S.; “A practical synthesis of bis(indolyl)methanes employing boric acid”, Monatsh Chem 2010, 141, 1001-1004.

  22. Yadav, J. S.; Reddy, B. V. S.; Yadav, N. N.; Gupta, M. K.; “Three component coupling of isoquinoline, activated alkyne and nitromethane: an expedient synthesis of nitroalkyl substituted 1, 2-dihydroIsoqunoline”, SYNTHESIS 2009, 1131-1136.

  23. Yadav, J. S.; Reddy, B. V. S.; Yadav, N. N.; Singh, A. P.; Choudhary, M.; Kunwar, A. C.; “Indium-mediated alkynylation of the Baylis-Hillman acetates: a novel route for 1,4-enynes”, Tetrahedron Lett. 2008, 49, 6090–6094.

  24. Yadav, J. S.; Reddy, B. V. S.; Yadav, N. N.; Gupta, M. K.; Sridhar, B.; “Gold(III) chloride catalyzed three-component reaction: a facile synthesis of alkynyl derivatives of 1,2-dihydroquinolines and isoquinolines”, J. Org. Chem. 2008, 73, 6857–6859.

  25. Yadav, J. S.; Reddy, B. V. S.; Yadav, N. N.; Gupta, M. K.; “Three-component coupling reactions of isoquinolines, dialkyl acetylenedicarboxylate and indoles: a facile synthesis of 3-indolyl-1,2-dihydro-2-isoquinolinyl-2-butenedioate”, Tetrahedron Lett. 2008, 49, 2815-2819.

  26. Yadav, J. S.; Reddy, B. V. S.; Yadav, N. N.; Satheesh, G.; “Aluminium(III)-promoted Prins-cyclization of 2-allylphenols: an expedient synthesis of benzoxepines”, SYNTHESIS 2008, 2733-2738.

National Journals:
International Conferences
Paper presented at international conferences